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The ultimate response to p53 activation and the contribution of various p53 activities is therefore likely to be strongly stimulus and cell type dependent.
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We found that directional selectivity during sustained stimulation with whisker deflection sequences depended strongly on stimulus frequency.
On the mother's side, an open-eyed newborn is a strongly reinforcing stimulus that affects the establishment of positive maternal responsiveness [39].
Brisk transient cells responded strongly to stimulus onset then adapted completely.
Finally, we note that timing of event-related signals depends strongly on stimulus properties (e.g., Bobak et al., 1987).
Recent fMRI studies (Buracas and Boynton 2007; Murray 2008) observed precisely such an "additive" interaction between attention and contrast in lower level visual areas V1, V2, and V3: Attention added an amount of blood oxygen level dependent (BOLD) activity that did not depend strongly on stimulus contrast (Fig. 1 C ).
They conclude from their 1998 study, as well as electrophysiological studies in V4 [47], [47], that V4 neurons coded more strongly for stimuli in their receptive field that matched the top-down goal rather than the absolute color of the stimuli.
Individual differences in autoantibody reactivities, if not due to chance variation, suggest that the healthy immune system can reflect quite subtle individual differences in development and environment, and not only responses to overt infections and other strongly immunogenic stimuli.
Perhaps the property of these neurons to respond strongly to stimuli of different modalities enables them to integrate olfactory information with other sensory information and aids in the formation of associative memory.
Thus, while most neurons in lateral intraparietal, arcuate, and principal sulci (LIP, FEF and area 46) respond more strongly to stimuli presented in the contralateral visual field, i.e. show a contralateral preference [but see 21], neurons representing any given polar angle within the contralateral field are relatively evenly distributed across the cortical surface.
Thus experiments in intact plants led to the original hypothesis and strongly support stimulus-induced Ca2+ sensitivity priming guard cells.
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