Sentence examples for strongly prognostic of from inspiring English sources

Other sets strongly prognostic of recurrence are the histones, the metallothioneins/16q13, as well as GAPDH, CD24, AFFX-M27830_5, and GNAS.

As with the three Affymetrix data sets, the histone and proliferation gene sets are strongly prognostic of poor outcome in the NKI data.

They found that this list is somewhat associated with diminished survival time for estrogen-positive samples, but is strongly prognostic of increased survival for estrogen-negative samples.

The proliferation set is strongly prognostic of recurrence in the Uppsala data, as it is in the other three data sets, which accords with a number of microarray-based studies of breast cancer [ 39, 40].

In an EORTC trial of temozolomide in the primary treatment of glioblastoma [ 1] MGMT methylation status was strongly prognostic for survival, and with a suggestion of a predictive effect [ 2] although this remains unproven within that trial.

Recently, the MRC COIN trial could not find an improvement in the OS or progression-free survival of mCRC patients treated with cetuximab, but they did show that NRAS, KRAS and BRAF were strongly prognostic regardless of cetuximab treatment (Maughan et al, 2010).

For example, proliferation-related markers are strongly prognostic and also predictive of chemotherapy sensitivity among ER-positive cancers but these same markers are not predictive in ER-negative cancers.

We report here the design of a GE-based risk score, involving 20 genes, whose value is strongly prognostic in 2 independent cohorts of CLL patients.

They went on to build a "stem cell score" based on the expression of these genes, which proved strongly prognostic in two independent patient cohorts [ 79].

However, none of these three markers were as strongly prognostic as DLEC1 and MLH1 methylation in this cohort.

A total of 181 genes belonging to 13 clusters strongly prognostic (HR = 3.26, P = 0.0002).