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Compared with earlier approach, our method strongly preserves the topology of a human model; more details can be constructed; and both the robustness and the efficiency of the algorithm are improved.
This leads us to design a generalized Paige–Tarjan algorithm, called GPT, for computing the minimal refinement of an abstract interpretation-based model that strongly preserves some given language.
Finally, we show how GPT allows to deal with strong preservation of new languages by providing an efficient algorithm that computes the coarsest refinement of a given partition that strongly preserves a language generated by the reachability operator.
This result supports the presence of strong purifying selection in anurans [ 23, 37], which strongly preserves mt gene function [ 65, 66].
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In males, 13 of the 35 modules identified were strongly preserved in females but seven modules showed very weak preservation (i.e. unique to males) (Additional file 5).
A module shows no evidence of preservation among datasets if its Z-summary statistic is smaller than two, whereas a statistics between two and 10 is corresponds to moderately preserved (reproducible) module, and above 10 is to a strongly preserved module [ 60].
We characterize the linear maps that preserve (strongly preserve) one of the majorizations or.
It is thought that the accumulation of misfolded structures for highly expressed proteins can severely damage the cell, so well optimized sequences leading to a high ratio of correct/incorrect three-dimensional structures are strongly preserved.
As observed in the case of other proteins [20], [21] whose structures were strongly preserved during evolution, functions can evolve independently and the present results reveal that it is necessary to reconsider the way we interpret the presence of TSPO in bacteria.
Only the yellow CN module was strongly preserved in both blood data sets.
In total, we find that five brain modules were strongly preserved in human blood.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com