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This strongly impairs the environmental friendly character of the resulting composite material.
The poor water solubility of vitexin limits its dissolution, which strongly impairs drug bioavailability.
Furthermore, retention of the NMD factor hUpf1 in the nucleus strongly impairs NMD.
Heat generated in electronic devices has to be effectively removed because excessive temperature strongly impairs their performance and reliability.
However, restricting the polypeptides to the nucleus strongly impairs their NMD-inhibitory function, even for those intended to inhibit interactions between the exon-junction complex (EJC) and hUpf3 proteins, which localize primarily in the nucleus.
Thus, we conclude that the breakdown of the vasculature in response to the antiangiogenic treatment strongly impairs the delivery of the probe to the tumor tissue, consequently resulting in a low probe accumulation despite the enhanced apoptosis.
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Dams strongly impair the fluvial environment by altering downstream flows.
The study also revealed strongly impaired error detection in schizophrenia.
Interestingly, the p38 MAPK inhibitor, SB202190, strongly impaired GW9508- or EPA-induced FGF21 gene expression.
Moreover, the capacity of CL316,243 to induce oxygen consumption was strongly impaired in GW9508-treated GPR120-null mice (Fig. 3a).
Feeding ability in bisected animals was strongly impaired after injury probably due to functional restoration of the gut.
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