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Six xylanases (XylA, XylB, XylC, XylE, XylF and XylG) exhibit amino acid sequence homology of around 11 ~ 52% and strictly conserve the two catalytic glutamate residues, and also strongly conserve other resides located in the speculative catalytic cleft (Paës et al. [2012]).
Unlike the versatile immunity proteins, these tend to strongly conserve an interface that facilitates a very specific interaction with their cognate type of toxin.
The fact that, in spite of the high variability the antisense transcripts strongly conserve the splice donors and acceptors sites suggests that this processing is important and points once more to a putative functional role.
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Positional analyses indicate that 53.6% of positions are very strongly conserved, ω = 0.0037, 40.6% are strongly conserved, ω = 0.1247, and 5.7% are conserved, ω = 0.9974 (Figure 1).
Whilst the miRNA sequence is strongly conserved between species, this does not necessarily guarantee conservation of their function [ 78].
Strongly conserved intron patterns, as well as distinctive patterns of sequence conservation, distinguish the six types of NTMC2 genes.
Asterisks indicate fully conserved nucleotides and dots indicate strongly conserved residues.
Among the predicted motifs (Table 1), AGCTAGCT was strongly conserved immediately downstream of TSSs (Figure 2G I).
We find that both developmental and housekeeping genes show highly dynamic and strongly conserved temporal expression patterns.
Focusing on the subset of strongly conserved residues, the average heavy atom RMSD is 2.6 Å (2.3 Å).
The data further indicate that procapsid assembly and maturation are strongly conserved in the prokaryotic and eukaryotic virus groups.
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