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The strongest functional knockdowns were observed for siRNA A1.
Based on functional classifications of these genes, SLIT3 is the strongest functional candidate due to its role in axon development.
Therefore, the IFIH1 nsSNP obviously remains the strongest functional candidate; however, the fact that it could be merely a marker of association that tags another variant regulating expression levels of IFIH1 or of neighboring genes, must be ruled out.
The absence of common nsSNPs in the other genes makes the IFIH1 SNP the strongest functional candidate, but it could be merely a marker of association, due to LD with a variant regulating expression levels of IFIH1 or neighboring genes.
Interestingly, groups with clusters enriched for TSSs distal to nearby genes show the strongest functional associations.
Coding region microsatellites are likely to be under the strongest functional constraint, and therefore be the least variable.
Similar(43)
Since modules often show strong functional coherence, the diverse set of annotations provide a complementary overview of module function.
Common words with strong functional associations (for example, a cook who will prepare food) are easier to retrieve than proper names (Mr. Cook).
The main theoretical result is a strong functional version of the Gauss Markov theorem.
Importantly, the limitation of BbAMA-1 diversity under strong negative selection indicates strong functional constraints on this gene.
The right insula and left inferior parietal lobule revealed strong functional connectivity in resting-state in a recent research [45].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com