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Stronger stabilization was observed with compounds containing linkers ending with amino functions.
FRET results showed that 1,3-disubstituted benzene derivatives had much stronger stabilization effect on G-quadruplex DNA than that of 1,4-disubstituted benzene derivatives.
In addition, the DPC derivatives showed much stronger stabilization activities and binding affinities for c-myc G-quadruplex rather than telomeric G-quadruplex.
This dynamical hindrance together with the stronger stabilization of proliferative progenitor states results in equilibrium distributions that are peaked at intermediate α-values.
One possible explanation for this difference is that in the mismatch-deficient M. tuberculosis, selection against unstable sequences is stronger than in E. coli, and that this results in a stronger stabilization of the genome by context-dependent codon choice.
Similar(55)
An LQ strong stabilization problem is proposed.
Then, the resulting microtubules were stable to Ca2+-induced depolymerization, indicating strong stabilization of microtubules.
Furthermore, the H∞ stable stabilization and strong stabilization problems can also be solved by relaxing certain constraints accordingly.
The binding of both the drugs was further characterized by strong stabilization of DNA against thermal strand separation in optical melting as well as differential scanning calorimetry studies.
The example also shows the effects of internal and input/output time delays on the solvability of the strong stabilization problem using this approach.
This paper investigates the problem of global strong stabilization by state feedback, for a family of high order feedforward nonlinear time-delay systems.
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