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Fig. 5D shows that a stronger origin association is found at TSSs of genes harboring Pol-II binding sites (t-test, p = 3×10−6).
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This defines DS as a strong origin of replication.
We conclude that the loss of a strong origin of replication can be compensated by the activation of multiple weaker replication initiation sites.
This was indeed the case for S. cerevisae, where NUMTs were detected as origins using conditions that slow down replication of the strongest origins.
"There is no other stronger source for the origin of the J-20's stealthy technology," said Huang, an expert on China's air force.
This show, as strong on origin stories as the museum's acclaimed surveys of performance art and conceptual art, should dramatically improve our collective memory.
These results therefore give a clear indication to the strength of supervector regression method in that it is able to generate much stronger same-origin comparison scores based on regression than the conventional GMM-UBM approach based on a ratio of probability densities.
Except for a few samples with strong Asian origin, we believe that most of the samples have minimal Asian admixture proportion.
Based on the risks by age difference, the younger teratoma component may be the most heritable familial component, whereas the later component of teratoma and seminoma may have a strong environmental origin.
"We realize that just opening markets for our textiles and apparel exporters is not enough, so the export opportunities in this agreement go hand in hand with strong rules of origin and strong textiles enforcement mechanisms".
This observation suggests the existence of a hierarchical order of strong dominant origins and, of an abundant number of rarely used weak auxiliary origins of DNA replication [39].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com