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We will show that the stronger diffusion plays a key role in deducing such a uniform bound.
Increasing the interfacial area through an emulsification process promotes a stronger diffusion of the compound from the oil core toward the interface.
Diffusion-weighted imaging in the abdomen and pelvis has been increasingly used since the 1990s with the development of stronger diffusion gradients, faster imaging sequences, and improvements in technology and MRI instrumentation [5].
In general, increased incorporation of DH in the intermediate layer or of XG in the outer layers reduced the drug release because of restricted and delayed exposure to the dissolution medium or formation of a stronger diffusion barrier, respectively.
The key component of a microstructural diffusion MRI 'super-scanner' is a dedicated high-strength gradient system that enables stronger diffusion weightings per unit time compared to conventional gradient designs.
First in vitro diffusion experiments (performed using an ATR-FTIR diffusion cell) of the hydrophilic compound, urea, revealed that the lipid model membrane represents even stronger diffusion barrier than the human SC.
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Diffusion-weighted images showed heterogeneous hypointensity without strong diffusion restriction [apparent diffusion coefficient (ADC) value = 1.39 × 10−3 mm2/s] (Fig. 2b).
Upwind schemes can cause strong diffusion and significant smearing in the solutions.
We attribute this behavior to strong diffusion of charges coming from the "hot-molecule" towards the interface.
b Diffusion-weighted echo-planar image (TR/TE, 2291/47 ms) shows heterogeneous hypointensity without strong diffusion restriction (ADC value = 1.39 × 10−3 mm2/s) (arrow).
SSFs are a type of spread-F that can be identified when there is strong diffusion on the frequency and height axis of an ionogram.
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