Sentence examples for strong upstream from inspiring English sources

When Pol II GOF alleles are combined with the strong upstream shifting allele tfg2 ∆146-180, the double mutants are inviable on this medium.

In mouse rpL30, a downstream YY1 interaction also contributed positively to transcriptional activity, but only when a strong upstream interaction with GABP was eliminated [ 11].

The CMV enhancer and promoter contained a canonical TATA box and a strong upstream activation sequence that together can initiate strong transcription.

No strong upstream motif was identified for this set, even though it is a tightly co-expressed set (Pearson correlation value, 0.88; Table 1).

H2A.Z at active promoters show strong upstream as well as downstream peaks in human and yeast [ 11, 17, 30, 55], but not in flies [ 56] or Arabidopsis [ 57].

The observed expression of the locus in Min-induced adenomas is consistent with the bioinformatic prediction of WNT-induced transcription from the strong upstream promoter P1 and the known action of APC protein to regulate WNT signaling.

It is shown that, for the range of conditions and microphone positions considered, the effect of turbulent loading on the radiated noise can vary from about 2 8 dB, being stronger upstream than downstream.

All genes in the genome were then ranked based on the strength of their strongest upstream site.

For each gene we plotted the strength of its strongest upstream Met4 binding site according to the model in Fig. 5 and its average expression change for induction and repression experiments (Fig. 7).

tfg2 ∆146-180 has stronger upstream shifts at ADH1 than tfg2 ∆261-273, whereas tfg2 ∆233-248 has little effect, consistent with the work of Eichner et al. (2010).

The strongest upstream shifting allele tfg2 ∆146-180 suppressed GalR phenotypes of all Pol II alleles that had the GalR phenotype, whether GOFs or LOFs; tfg2 ∆233-248, an allele with no apparent ADH1 TSS defect, enhanced GalR phenotypes of weak Pol II GOF alleles.