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The beginning of lactation might be a strong stressor for every cow.
Loud white noise can be a strong stressor (Lai 1987; Cheng et al. 2011).
Hence, down-regulation of SSB1/2 in the mistranslating cells likely increases accumulation of misfolded proteins, which may explain why cells integrated mistranslations as a strong stressor.
However, expression profiles in this study revealed that short-term hypercapnia (10-fold increase in seawater pCO2) does not act as a strong stressor on gill tissues.
The response of Carcinus maenas to elevated seawater pCO2 based on the gill transcriptome does not suggest that seawater acidification acts as a strong stressor for the western Baltic population of this species.
Plasmodium infection is therefore not detected by hepatocytes as a strong stressor necessitating global translational repression in response, highlighting the idea that Plasmodium has evolved strategies to ensure its remarkable growth in the hepatocyte while maintaining host cell homeostasis.
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Some resilient children were especially unlucky: they experienced multiple strong stressors at vulnerable points and their resilience evaporated.
Only strong stressors, like very high iron or H2O2 concentration in the medium have shown to possibly up-regulate SOD2 in FRDA fibroblasts [31] by triggering NFκB signaling.
In older patients, cancer treatments, especially chemotherapy, are considered strong stressors that will reveal which patients have sufficient functional reserve to regain stable homeostasis [ 3, 17].
The strong predation stress in the Savanna, and the harsh topography that members of Caprini inhabit as compared to the Euro/Asia Bovid habitat, can be strong stressors that favor a shorter involution period.
In addition, moderate and strong stressors such as swimming and restraint initiate a fast increase (within 5 min) of circulating CBG, keeping free corticosterone concentrations attenuated for about 20 min.
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CEO of Professional Science Editing for Scientists @ prosciediting.com