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Here we explore networks with strong recurrence in a computational model and show that short-term depression of the synapses in the recurrent loops implements an adaptive filter.
Mutations in the BRCA1 and BRCA2 tumour suppressor genes have been associated with the breast cancer risk among families with strong recurrence of the disease [ 4- 9].
In a previous population-based study we described the first example of a founder BRCA1 mutation in Italy, with a strong recurrence of the 5083del19 in high-risk patients all of Calabrian origin selected for family history of the disease [ 1].
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Of the two cleft categories, the QQ plot for I-CP showed the least evidence of association with the selected SNPs, yet this is the cleft subtype with the stronger recurrence risk in families [79].
Our data suggest that cerebral palsy includes a genetic component, with a stronger recurrence among relatives with closer genetic relationship.
The estimation of risks within a single study also makes the pattern of stronger recurrence among closer relatives more interpretable, being less susceptible to bias from alternative methods of case ascertainment in diverse smaller studies.
The preoperative blood spillage of prostatic cells show a strong biological recurrence predictive power, which is independent of other classical markers such as blood PSA initial levels.
First, throughout the follow-up assessment visits, no patient presented with a strong exudative recurrence, which indicated that the planned intervals were appropriately tailored to treat nAMD in each individual.
At least 50 of the 390 EPN target interactions (comprising 25 miRNAs and 35 mRNAs) have strong evidence of recurrence in multiple cancer types (recurrence score < −3.0 and FDR < 0.05) on the basis of The Cancer Genome Atlas (TCGA) miRNA-target interactions analysis across 10 cancer types [ 9].
Additionally, uPA has been described as a strong predictor of recurrence after radical prostatectomy [ 26– 28].
Hence, CMTC is an independent, strong predictor of recurrence in breast cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com