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This signal peptide (secrecon) directs strong protein secretion and expression.
The thiourea derivative YH345 A has shown strong protein farnesyl transferase inhibition activity [17].
We found no β1 nAChR subunit mRNA expression in the human and piglet brain despite strong protein expression.
Indeed, strong protein bands corresponding to CD147EC dimer and even high-order oligomers could be detected on the SDS-PAGE (Fig. 1E).
For gene expression in mouse thyroid tissue, '+' indicates gene expression, whereas for protein expression, '+', '++', or '+++' indicates weak, moderate, or strong protein expression levels, respectively.
We hypothesized that this may be due to a bottleneck in the protein secretion pathway caused by too strong protein expression as a result of mixed feeding operation.
This technique consisted in loading feed mixtures dissolved in a good solvent onto the column by several small-volume injections under conditions of strong protein adsorption.
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Finally, co-immunoprecipitation studies revealed a strong protein-protein interaction between LRP1 and PKC-δ in the CP.
A highly similar gene in petunia (PhTM6) also showed stamen expression and strong protein-protein interaction with the petunia PHGLO2 polypeptide [ 66].
The crystal structures demonstrate the extensive clustering of Lys side-chains at the protein surface opposite the heme pocket that accomplishes the strong protein-membrane interaction.
Structural analyses of this protein, suggest that it harbours a β-grasp motif that can form strong protein-protein interactions [ 35, 36].
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