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The peaks for the aldehydic moiety were not observed in the final products after being converted to the imine (C=N) group which is also a strong proof for the successful synthesis of the target compounds.
The obtained result provided strong proof for the role of STAT5b in invasion (Fig. 4c).
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The highly encouraging results from this comprehensive evaluation of antiretroviral PrEP efficacy serve as strong proof of principle for this approach and have major implications for the continued planning and implementation of future and current PrEP studies.
An alternative and stronger proof for dopamine mediation of action syntax would be to demonstrate enhanced stereotypy of behavioral sequences, by boosting nigrostriatal dopamine neurotransmission.
Regardless of the human connection, experts agree that the study offers strong proof of the meat-for-sex theory, which had previously been highly debated.
These results provide a strong proof of concept for engineering photocatalytic hydrogen production in the presence of oxygen using biohybrid mimetic systems.
24 The success of these approaches represents a strong proof of principle for the potential utility of microneedle platforms providing either rapid delivery or sustained release of therapeutics to the skin.
The results reported here provide a strong proof of concept for supplanting the provision of costly medium components through co-culturing that can be optimized through metabolic engineering and implementation of enhanced acetate-producing cyanobacteria.
Liver repopulation with functional BM-derived hepatocytes in genetic liver disease, a result of fusion between donor BM-derived cells and host hepatocytes, has already been shown in animal models, thereby providing strong proof of principle for targeted organ regeneration through exploiting cell fusion events [ 47].
While some other 2-drug ART regimens that have previously been tested as initial treatment of HIV have proven inferior to 3-drug ART, strong proof of concept for this 2-drug maintenance approach was provided by data from the Long-Acting Antiretroviral Treatment Enabling (LATTE) study.
It was strong proof of the value of Medicare's universal coverage for elderly Americans.
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