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For example, SF162 was generally easier to neutralize than other viruses, showing strong neutralization by 447-52D, but much less so by 4E10.
Secondly, the simulation results of April 1995 exhibited a strong neutralization of the precipitation by the yellow sand.
We generated anti-H IgG MAb 20H6 with a strong neutralization capacity >1 80,000 at 1 mg/ml concentration in MV plaque-reduction neutralization assay.
The cells range from green representing weak or no neutralization (IC50>25 µg/ml; >10 µg/ml for sCD4) to red representing strong neutralization (IC50<1.0 µg/ml).
The combination of strong neutralization and reduced pathogenesis in the rhesus macaques indicates that the approach is worth pursuing.
Eleven of the clones exhibited strong neutralization potential (∼95% or higher) at 100 nM; among these, E10 and F4 had favorable expression yield, were well-behaved, and thus were carried forward for further studies as representative examples.
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Antibodies from sera of animals administered with a monoglycosylated HA molecule exhibited higher binding affinities for native HAs and stronger neutralization of the virus.
This preference is more evident in clones showing stronger neutralization efficacy (below).
We also confirmed the neutralizing activity of the plant-derived mAb in the FAVN assay and observed strong RV neutralization (500 IU/mg), similar to the previously reported potency of its murine hybridoma-derived counterpart (6).
This figure reveals that Fe ions have a longer lifetime compared with Na+, which will result in a more rapid neutralization of the latter resulting in stronger neutral Na sporadic layers compared with the former.
All inoculated animals tested for seroconversion at 14 28 dpi had a strong detectable neutralizing antibody response to WNV (100% neutralization by 1 10 serum); there was no noticeable effect of strain used for inoculation (n = 6 sparrows, 3 grackles, 7 thrushes).
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