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Scientists have found that when a T cell recognizes a foreign protein fragment, that by itself is not enough to set off a strong immune response.
It's used in the vaccine because scientists already know that the human body is able to mount a very strong immune response against it.
Other H7 vaccines have not created a strong immune response, according to Michael Osterholm of the University of Minnesota.
Experience has shown, however, that although there is a strong immune response to the intact virus with its unexpanded shell, the expanded shell passes almost unnoticed.
In a small, preliminary study, an experimental vaccine provoked a strong immune response against precancerous cells in women treated for cervical lesions that can progress to cancer.
Because tumor cells are mutated forms of the body's own cells, not an invading pathogen, they do not usually elicit a strong immune response.
But for reasons still not clear, some cancers, including prostate, don't activate a strong immune response.
Thus, depending on the cytokine milieu, DCs can elicit a strong immune response or a tolerogenic state.
In this study, we have identified a G. lamblia protein that induces a strong immune response in infected mice.
And only 29% had antibodies that could activate T cells--a necessary part of a strong immune response.
She hopes that this strong immune response will prevent the polyps from either recurring or reverting to colon cancer.
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