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The "cotton model" suggests strong duplicate gene conservation that extends well into the intergenic regions.
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Of the zebrafish gene orthologs in this study, however, we find that only two genes show strong evidence of duplicate gene maintenance – titin and FLNC – with at most four gene duplications suggested by the genomic sequence (including dysferlin and desmin).
The HAMP plan will probably keep some borrowers from losing their homes but it won't duplicate strong economic growth, say the RBC analysts.
Sample A (A) and sample B (B) from two patients both showed strong correlations between duplicate samples on different chips and different profiling day in discovery study (R 2 = 0.99), indicating that detectable miRNAs (after meeting quality control criteria) are experimentally consistent.
There was also strong agreement between duplicate samples (correlation coefficient R=0.975) and between independent operators reviewing the same digital images (correlation coefficient R=0.994).
In this paper, we conducted an extensive and careful analysis for the mouse KO phenotype data and corroborated a strong effect of duplicate genes on mouse genetics robustness.
Z. Su et al. performed an extensive analysis of the mouse knockout phenotype data and corroborated a strong effect of duplicate genes on mouse genetics robustness.
We have recently demonstrated that the duplicated region contains a weak melanocyte-specific enhancer that becomes a strong enhancer when duplicated [ 18].
Total expression (T) is the strongest predictor of duplicate gene functional persistence after WGD out of the parameters we considered.
The distribution of putative evolutionarily young human gene duplicates is strongly L-shaped with the highest density of gene duplicates occurring in the youngest age cohorts and a strong decline in gene duplicate frequencies with increasing synonymous divergence.
As shown in Figure 5, even after removing all essential genes, the KO duplicates still show strong age bias toward ancient duplicated genes.
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