"strong difficulties" is a correct and usable phrase in written English.
You can use it to refer to any challenging situation that is particularly difficult to overcome. For example: "The team has been facing some strong difficulties while trying to reach their goal."
Another strong difficulty to overcome is existing: the strong difference of scales between the wavelength of the focusing laser spot size (currently close to the micrometer range) and the nanostructures sizes (close to the nanometer range).
However, prior research has often neglected the external mode of knowledge exploitation despite the contradictory situation that some pioneering companies realize enormous benefits whereas most other firms experience strong managerial difficulties.
We point out that, in order to obtain our continuation result for RFDEs with infinite delay without assuming the compactness of the ambient manifold M, we had to tackle strong technical difficulties.
Although some of these methods have convenient protocols with good to high yields, the majority of these methods suffer at least from one of the following disadvantages: reaction under oxidizing conditions, prolonged reaction time, high temperatures, use of moisture-sensitive and expensive catalysts, use of solvents, strong conditions, difficulty in scaling up, etc.
Twin model fitting suggested that the degree of genetic overlap was particularly strong between communication difficulties and traits of ADHD (genetic correlations = .47−.51), while repetitive behaviours and social difficulties showed moderate (genetic correlations = .12−.33) and modest (.05−.11) genetic overlap respectively.
And while the Northwest's overall economy remains strong, Asia's difficulties have led some government officials to project a noticeable slowdown in growth.
While easyJet's losses are significantly higher than the £68m fall into the red in the first half of 2018, the airline's performance a year ago was unusually strong, benefiting from difficulties experienced by its biggest competitor, Ryanair, and the collapse of Monarch, as well as an earlier Easter.
The landing was delayed by a strong current and difficulties forming the LVTs into an assault formation, and the first wave went ashore at 7 28 am rather than 6 30 am as planned.
Depletion of CENP-V causes a strong CPC phenotype (difficulties in chromosome bi-orientation and a failure to complete cytokinesis) that is rapidly followed by apoptotic cell death.
