Exact(13)
In contrast, EL3'-11 with 1 single-stranded extension induced strong cleavage in total RNA extracted from yeast (lane 8) but not in cell extract (lane 4).
Using G5 (where a strong cleavage activity was first observed) as our starting pool, a new selection experiment was conducted with the modified selection scheme, in hope of isolating DNAzymes that are Mg2+-dependent and more efficient than G12SD.
This result was confirmed by the strong cleavage of PARP on DC treated with gangliosides.
In neuronally differentiated SH-SY5Y cells, KU-55933 induced strong cleavage of PARP and Caspase-3 even in the presence of insulin, indicating the occurrence of apoptosis.
The enzymatic activity of caspases shows strong cleavage site specificity towards a four amino-acid motif ending with an aspartate residue [ 19- 21].
pFAN1 exhibited a different profile with strong cleavage 4 and 5 bp after the branchpoint but with no detectable cleavage at the 5′ end.
Similar(47)
This is consistent with IDE's strong cleavage-site preferences at P1' and P2' and weak preferences at P3' and P4' (Fig. 1A).
Consistent with previous report (17), the rEGSx library gave much stronger cleavage than the rEGSe library (Fig. 1A).
In contrast, prestimulation with ABT737 allowed stronger cleavage to the p17 fragment concomitant with increased PARP-1 cleavage.
We find that the strongest cleavage peaks approximately correspond to the left-hand preferred cleavage sites seen for Cen4 in vivo (Materials and Methods section "In vitro cleavage mapping" new Figure 4 figure supplement 1).
In contrast, silencing of Ephrin B3 in combination with IR initiated a strong PARP cleavage at 48 h post IR and at 120 h post IR this combination induced the most pronounced PARP cleavage of all samples.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com