Sentence examples for strong bone resorption from inspiring English sources
Analysis of tumors from this model revealed that they exhibited strong bone resorption, induction of osteoclasts and intracranial penetration at the tumor bone (TB -interface.
By micro-CT, high molecular weight chitosan induced a particularly strong bone resorption at 0.5mm and 1.5mm depths (p<0.05, 150K vs 40K hole area, Figure 9B), which was consistent with histomorphometry measures in collagen type I-stained sections showing a larger area of granulation tissue in 150K-treated defects than in both 40K and 10K-treated defects after 21 days (p<0.05, data not shown).
Recently it has been suggested that apoptosis of osteocytes results in strong osteoclastic bone resorption.
A recent study with odanacatib, a specific cathepsin K inhibitor, has demonstrated a strong decrease in bone resorption, an initial drop in bone formation, which subsequently increased towards the baseline level [ 58].
Minodronic acid hydrate shows the strongest inhibition of bone resorption among all the bisphosphonates used for osteoporosis treatment in Japan.
62 Eldecalcitol possesses a strong inhibitory effect on bone resorption and causes a significant increase in BMD.
This study found a strong inhibitory effect on bone resorption by bisphosphonates but also a limited inhibition of the ingrowth of new bone.
Our results suggest that treatment with denosumab causes a strong inhibitory effect on bone resorption markers and mild inhibitory effect on bone formation markers.
In conclusion, denosumab has a strong inhibitory effect on bone resorption markers, although its inhibitory effects on bone formation markers are weak.
Hence, denosumab has strong inhibitory effects on bone resorption at an early stage after therapy commencement, regardless of BP pre-treatment.
In addition to regulation of calcium metabolism carried out by conventional vitamin D analogs, eldecalcitol possesses a strong inhibitory effect on bone resorption and causes a significant increase in bone mineral density.
