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H. insolens EGV shows a strong binding preference for dislocations compared to the surrounding normal cell wall.
The control CA/07(H1N1) virus exhibited a strong binding preference for α2,6-linked sialic acids (α2,6-SAs).
Similar to Beclin 1 ECD, this LC3 variant also exhibited a strong binding preference for liposomes enriched with cardiolipin.
In contrast, MDk/W452(H5N8) as well as the authentic HPAI A(H5N1) viruses showed a strong binding preference for α2,3′-SL-PAA-biotin residues.
Instead, it showed a strong binding preference for sialic acids with α2,6 linkages, with minimal binding to sialic acids with α2,3 linkages.
Lastly, DSL exhibited a strong binding preference for kidney hGGT1 and a modest interaction with liver hGGT1, yet this lectin exhibited no apparent affinity for Pichia pastoris-expressed hGGT1.
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The differential hemagglutination titers achieved suggested that Alb/58 virus possessed stronger binding preference for α2,6 SA in comparison to α2,3 SA receptors, whereas Mallard/78 virus appeared to possess comparable preference for both receptors in this assay (Table S1).
Many known GTP-binding proteins, including multiple heterotrimeric G proteins, exhibit a strong binding preference toward SGTP.
Only Humicola insolens EGV was found to have stronger binding preference to dislocations than to the surrounding cell wall, while no difference in binding affinity was seen for any of the other cellulose variants included in the study (H. insolens EGV variants, Trichoderma reesei CBHI, CBHII and EGII).
We developed a robust pipeline to identify candidate "seed" regions that clearly showed a stronger binding pattern based on specific positions, restricting it to the 5' or 3' end and a binding preference for 3' UTRs.
We constructed the binding preference of each TF with a simple heuristic which assesses the binding preference for a TF from a set of known binding sites.
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CEO of Professional Science Editing for Scientists @ prosciediting.com