Sentence examples for strong binding affinity for from inspiring English sources
Additionally, molecular docking results showed a strong binding affinity for compounds 1 3 through chelation between copper metal and ligands.
We further performed detailed analysis on the amino acid contributions to the binding energies and found that the strong binding affinity for 6F-tricin to CDK9 is attributed to the specific binding orientation of 6F-tricin in the ATP-binding site.
As a DNA cleavage domain, we chose an analogue of the metal-binding loop (12 amino acid residues), peptide P1, which has been reported to exhibit a strong binding affinity for a lanthanide ion and DNA cleavage ability in the presence of Ce(IV).
In this process, a water-soluble polymer with strong binding affinity for the target metal ions is added to contaminated water.
We chose a FUNDC1 LIR peptide10 25 with pS17, which simulates the possible physiological state upon the induction of mitophagy and exhibits a strong binding affinity for LC3B, to co-crystallize with full-length LC3B1 125.
Strep-tag II has a strong binding affinity for an engineered streptavidin derivative called Strep-Tactin, which enables fast and simple one-step purification [34].
Second, we simulated the binding kinetics of a model library binding to a model target molecule within our device and discovered that aptamers with strong binding affinities for the target (i.e., equilibrium dissociation constant KD = 0.5 nM) were preferentially retained at the input end (i.e., in the first few microliters) of the microfluidic column.
Most (∼80%) of the intracellular ATP pool exists as a Mg2+ chelate, owing to the strong binding affinity of ATP for Mg2+.
Therefore, PNA can highly discriminate mismatched DNA and has a stronger binding affinity for complementary DNA than does its DNA counterpart.
Surface plasmon resonance analysis and luciferase assays showed that the T allele demonstrated a stronger binding affinity for miR-25 and miR-32, resulting in significantly weaker reporter expression levels.
Bundibugyo GP showed the strongest binding affinity for hTIM-1 Ig V with a dissociation constant (K d) of about 4.9 μmol/L, while GP and RBD from Zaire exhibited similar binding affinities for hTIM-1 Ig V (Fig. 2B D).
