Sentence examples for strong arrest from inspiring English sources

Such results are also consistent with the finding that UV irradiation in G1 of a cycling rad14Δ strain results in a strong arrest at the beginning of S phase [58], accompanied by the accumulation of replication-dependent ssDNA regions [51].

Pre-treatment of HT-29 cells with CQ resulted in strong arrest of cells to the G0/G1 phase of the cell cycle, compared with cells treated with 5-FU alone (percentage of cells in G0/G1-phase: 65.1% vs 79.0% for 5-FU alone vs CQ and 5-FU, respectively).

Our in vitro cell cycle analysis on B16F10 had showed a strong G1 arrest as a result of AECHL-1 treatment.

These are all proteins known to play essential roles in mitosis, which, if completely knocked down, should on their own cause very strong mitotic arrest.

Interestingly, in growth experiments (Fig. 3B), the Ste2-Fz1/2(i) receptor chimeras exerted strong growth arrest in the absence of added α-factor, and the effects were stronger than observed for the Frizzled constructs described before (s-Fz1/2; Fig. 3A).

It has been reported that COMA plays a similar role [43] but this seems unlikely to us since mutations in essential COMA subunits such as ame1-4 and okp1-5 provoke a strong mitotic arrest under non-permissive conditions [7], [43].

Many kinetochore mutants provoke a strong checkpoint arrest (e.g., cse4-1, scmif2-3mif2-3, ame1-4, okp1-5, nnf1-17, mtw1-1, stu2-277, dam1-1) but a subset does not (e.g., ndc10-1, cep3-1, spc25-7, ndespite deseveresevere defects in chromosome-MT binding.

Strong growth arrest paralleled with PFUS1-reporter activity was also observed for the converse receptor chimeras, s-Fz1/2-Ste2(i), which employ the Ste2-intracellular portions, expected to afford good coupling to yeast Gpa1p.