Sentence examples for strong alteration from inspiring English sources

We used the gene for ARHGAP9 as a positive control for HP1β chromatin immunoprecipitation since this gene showed strong alteration in expression without showing evidence of altered expression subsequent to altered GRPR signaling, as determined by microarray, indicating that HP1β was likely binding in the vicinity of this gene.

High element concentrations and increased salinity are caused by strong alteration processes, along with high dissolution rates in the center of the geothermal field at Argopuro.

Only pollen dispersal was considered as a pathway with a profound impact potential, while other pathways were regarded as being less relevant due to spatially and temporarily limited GMO release and the strong alteration (e.g. decomposition) of GMO material in dung, manure or sewage sludge.

We identified a strong alteration in regulation of genes related to iron homeostasis, including multiple cytochrome P450s, heme biogenesis and metabolism proteins, and others.

We recently reported that LRP-1 silencing severely impaired the invasion of malignant cells consecutively to a strong alteration of cell-matrix interaction turn-over.

However only two of the variants in the mature miRNA sequences exhibit a strong alteration in the in vitro functional assays that measure a subset of miRNA function; the in vitro function in two other variants with alterations in the pre-miRNA is also affected.

Subsequent electron microscope investigations of chromatin structure showed strong alterations in the ultrastructure of the nucleus caused mainly by the heat denaturation step.

Such a deposition process induces an ion bombardment of the growing films: energetic ions can sputter atoms from the near surface of the coatings, leading to strong alterations in the microstructure of the deposited material.

These inflammatory mediators trigger strong alterations in brain development and changes in microstructural integrity [ 7].

Strong alterations in gene expression were also observed for the IGF axis.

Strong alterations in gene expression were also observed for insulin-like growth factor-I (IGF-I) the serum level of which correlated well with body weight.