Moreover, the loss of functional changes in the two major tumor suppressor proteins pRB and TP53 activities induced a strong activation of ribosome biogenesis in cancer cell [24].
Short-immunomers show strong activation of NF-κB and stress-activated signaling pathways and induce cytokines in J774 cell cultures.
Although a strong activation of PKA leads to IPC cell death, the basal activity seemed necessary for growth.
Transcriptomic changes induced by the virus involved strong activation of genes associated with interferon and tumour necrosis factor related responses and acute inflammation.
The expression of lethal doses of MEKK1 resulted in a strong activation of all three major MAP kinase families JNK, ERK, and p38.
Foremost, the contrast revealed a strong activation of the amygdala.
Cluster 1 consists of cell lines with strong activation of both EGFR and MET signaling.
Importantly, TNFα stimulation alone results in strong activation of the IκBζ promoter without subsequent protein expression.
Strong activation of both phospho-Akt and phospho-Erk1,2 was observed (Figure 6B).
SCF induced a strong activation of STAT5 in the MEP, but not in the HSC.
This mutation results in a strong activation of B-RAF, constitutively stimulating the MEK-ERK signaling pathway.
