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But, despite some positive reviews, the Apple feature didn't happen, and the media attention the game received has focussed almost exclusively on its potential as stroke therapy.
ImaRx Therapeutics of Tucson, Arizona, has just begun a trial of its own bubble-based stroke therapy, which it is branding as SonoLysis.
The company has studied treatment of major depression and the chronic ringing in the ears called tinnitus by stimulating various regions of the cortex, but it had bet heavily on reaching the market first with stroke therapy after initial research produced promising data.
To date, the only widely used drug in acute stroke therapy is the clot-dissolving agent tissue plasminogen activator (tPA), approved by the Food and Drug Administration in 1996.
From 1955 2000, 49 neuro-protective agents for stroke therapy have been tested in 21,445 patients.
Generalisation to a broad range of racial groups should be considered when conducting large international trials of stroke therapy.
Stroke therapy may be optimized by combination therapy with both a neuroprotective neurotrophin and an anti-inflammatory agent.
The TEMPiS project has shown to deliver high experienced stroke therapy to underserved areas and proved cost-effectiveness in hospital settings [47].
Using nuclear magnetic resonance (NMR) and fluorescence assays, we screened a collection of 58 TCM drugs that are commonly used in stroke therapy for caspase inhibitory activity.
Further exploitation of knowledge of neural transplantation therapy already available from our experience in treating Parkinson's disease needs to be critically considered for stroke therapy.
There is a lack of awareness that acute ischemic stroke therapy exists and that it must be used in an urgent fashion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com