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Variants with minor allele frequencies (MAF) less than 0.05 were excluded, and subsequent genomic control11 was applied to stringently control the global false positive rate.
The Never Again movement has pointed to a particular danger of the failure to stringently control access to firearms: the contagion of violence at the hands of individuals who never should have had access to weapons.
We previously showed that lentiviral vectors (LV) can be made responsive to miR to stringently control transgene expression as well as to report miR activity "live" and at the single-cell level.
Thus, KSHV has devised multiple mechanisms to stringently control RTA expression and activity, thereby keeping lytic replication in check.
Therefore, by controlling the levels of PtdIns(4,5 P2 and PtdIns 3,4,5 P3, PI3K and PTEN thus stringently control the signaling from phosphoinositides defining epithelial plasma membrane identity and epithelial polarity.
In the past years, pancreatic stellate cells (activated myofibroblasts; PSC) have been identified as major determinants of pancreatic fibrosis: they have been shown to be the major source of extracellular matrix production[10], [11] and to stringently control the balance of ECM secretion and digestion by producing matrix metalloproteinases and their corresponding inhibitors[12].
Similar(47)
The failure of vancomycin to increase synthesis of the stringent factor ppGpp while modulating expression of many stringently controlled genes suggests the former, but simultaneous induction of transcription of σB and the σB regulon, and of σE and the σE-dependent gene SCO3202, by all three antibiotics would be indicative of the latter.
These materials, overseen by the N.R.C. and the Department of Energy, are stringently controlled under the Atomic Energy Act.
The rpoB mutants destabilizing initiation complexes at stringently controlled promoters behave like 'stringent' RNA polymerases in Escherichia coli.
We show that the new method stringently controls the false discovery rate and asymptotically selects the correct biological model.
Running on a simple algorithm, the system stringently controls the thickness of each of the multilayers thereby avoiding thickness error build up throughout the deposition process.
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