With a mortal hero, Arindal, who is subjected to stringent trials, and his beloved, the half-mortal, half-fairy Ada, who first appears to him as a doe and is later turned to stone, the convoluted plot of "Die Feen" is a kind of distant precursor of Strauss's "Frau ohne Schatten".
Improved understanding of pathophysiological mechanisms, in conjunction with more innovative but stringent clinical trial design, will ultimately lead to improved patient outcomes.
The approach also enables use of sparse and unstructured real-life data, rather than relying on data derived from stringent clinical trial settings [ 15].
The country is now implementing a system of state-regulated legal highs, all of which will have to pass stringent clinical trials to be deemed "safe" for human consumption.
Building on this achievement, we present here the results of a more stringent bovine intervention trial (2004 2007) we undertook using a cluster-randomised design with increased power and with more general applicability to the lake and marshland regions of southern China.
They used very stringent criteria for trial inclusion, but nonetheless, on this point there is considerable consistency between reviews.
Like in a traditional Randomized Controlled Trial, stringent inclusion and exclusion criteria were applied to select the patient sample of the present study [Appendix, 'Inclusion and exclusion criteria of the patients', [ 17].
Stringent criteria for trial participation increase confidence in the validity of research results while reducing the generalizability of results to "average" patients with type 2 diabetes receiving care in community-based practices.
However, Chinese researchers are trying to study some TCM medications in stringent randomized controlled trials to assess its efficacy and safety.
