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GCA displays a stringent tissue tropism for certain vascular territories.
The disease is characterized by a stringent tissue tropism; meaning that granulomatous wall infiltrates typically appear in arteries of selected vascular beds.
CYP genes show varying degrees of tissue selective expression with some expressing widely in many tissues, whereas others showing stringent tissue specificity.
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However, a few BDTPs were not detected, possibly due to stringent tissue-specific expression patterns that did not include the embryo.
Our analyses suggest that the paucity of X-linked tissue-specific genes may be driven by the general inefficiency of stringent tissue-specific gene regulation on the X chromosome.
Owing to the stringent requirements of tissue engineering, a number of key characteristics need to be met by the polymer.
However, the affinity-purified polyclonal anti-MBP used in the present study 17 appeared to be more stringent in detecting tissue eosinophils.
Thus, complementary expression is a less stringent form of tissue-specific reciprocal expression, when compared with silencing.
Interestingly, GLM analysis indicated that more than 300 of the 1,971 gene pairs exhibited a less stringent form of tissue-specific reciprocal silencing (fig. 6).
To overcome the limited access to human neural tissue and stringent species specificity of HCMV, we used engineered neural tissues to: (i) provide a technical advance to mimick features of HCMV infection in a human neural fetal tissue in vitro and (ii) characterize the molecular and cellular phenomenon following HCMV infection in this tissue.
This might be explained by the more stringent conditions used for tissue homogenization.
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