Sentence examples for stringent specificity from inspiring English sources

However, the transition state of MtBPL probably selects the specific acceptor molecule which in turn explains its stringent specificity for its cognate BCCP.

TLR13 recognizes a stretch of conserved nucleotides from bacterial 23S ribosomal RNA with stringent specificity to trigger an immune response (Song et al., 2015).

While, some GTs with broad spectrum of substrate specificity are promising candidates for glycoengineering while others with stringent specificity pose limitations in accepting molecules and performing catalysis.

When stringent specificity information becomes available for as many enzymes as possible, accuracy of the prediction will also increase.

Display of a stringent specificity for its substrate is probably very critical for MtBPL due to the presence of different paralogs of BCCPs (accA1, accA2, accA3) in its genome.

However, given its relatively low read coverage, it did not meet our stringent specificity threshold.

It is becoming increasingly evident that certain viral proteases have more stringent sequence specificity.

Tobacco etch virus protease (TEVp) is a unique endopeptidase with stringent substrate specificity.

In vivo, this methylation is sufficient to protect the host DNA from cleavage by the cognate restriction endonuclease, R.EcoP15I, because of the stringent cleavage specificity requirements.

Like I-DmoI, H-DmoC2 is thermostable and cleaves the new target DNA to generate the predicted 4 nt 3′-OH overhangs but, unlike I-DmoI, H-DmoC2 retains stringent cleavage specificity when substituting Mn2+ for Mg2+ as co-factor.

Noticeably, HqD from strain SJ98 also showed stringent substrate specificity in the activity assay and is selectively induced during growth of strain SJ98 on PNP; these observations clearly indicate it to be involved in transformation of HQ produced during PNP catabolism by strain SJ98.