Sentence examples for stringent sequence from inspiring English sources

Exact(28)

It is becoming increasingly evident that certain viral proteases have more stringent sequence specificity.

However, increasing the sequence depth also directly affects the false discovery rate due to sequencing errors, further emphasizing the need to use stringent sequence quality parameters.

Using a stringent sequence similarity criteria as in [21], we identified 95 pairs of transcription factor (TF) gene paralogs for which there is a DNA binding site motif (Positional Weight Matrix or PWM) derived from human binding sites in the TRANSFAC database[18].

Since the increase in order of the Markov model implies that a more stringent sequence property is used to calculate compositional differences, a higher order model will in general give a more accurate representation of the sequence than a lower order one.

We further filtered our predictions using stringent sequence similarities as well as likelihood tests.

In many cases such functionally distinct can be removed by suitably stringent sequence similarity filters.

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Similar(32)

Mecham et al. have suggested that the lack of concordance in cross-platform microarray comparisons may be caused by a reliance on gene annotations without more stringent sequence-oriented matching of probes [ 23].

By using more stringent sequence-analysis criteria in a quality-improving protocol, we removed contaminated tags matched to cloning linkers, vectors, and simple repeats, and obtained 68,462 unique empirical tags; this number is 21 tags less than the previous dataset due to more stringent filters.

Appropriate contamination controls and stringent sequencing protocols were in place to assure the authenticity of recovered sequences.

It is comprised of three modules that solve the annotation process with progressively less-stringent sequence similarity requirements, combined with methods to optimize specificity.

Third, because the UniFam families were built from proteins with stringent whole sequence alignment requirement, we believe the genome annotation by UniFam is reliable.

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