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Mathematical modelling is a tool that allows asking the most stringent questions concerning the dynamic behaviour of predicted gene regulatory networks; it also quickly uncovers the restrictions and shortcomings of assumed interaction maps, and thus provides guidance to direct future experiments.
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ChIP-seq data is imperfect, however, so we regarded that criterion as too stringent – especially for questions of co-localization.
But some passengers who endured the most stringent requirements this weekend questioned whether they were really effective.
There would be "stringent security arrangements" and questions over the fate of Palestine refugees would be "solved within the state of Palestine or by resettlement outside .This amounts to the old "Clinton Parameters" which Mr Barak, then prime minister, accepted, but the then Palestinian leader, Yasser Arafat, rejected ten years ago in talks chaired by the then American president.
New research leads many heart disease experts to suspect that the guidelines for lowering cholesterol may not be stringent enough, raising the question of how low levels should be.
The admission patterns, known to be rapidly favorable, prevail, raising the question of more stringent admission criteria applied by physicians.
This finding also questions the relevance of stringent follow-up after several years have elapsed.
There is cause to rejoice in the fact that stringent belt-tightening is now being questioned as the best way to pull Europe out of its doldrums.
In response to a question about Arizona's stringent law, he said, "Arizona had a constitutional right to pass that law.
The case, Dr. Schaffner said, raises the question of "whether the stringent procedures that were initially put in place have eroded somewhat".
It begs the question of whether more stringent reporting laws would have made a difference in the Penn State sex scandal.
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