CBP has highly stringent potential AKT phosphorylation sites at Ser381, Ser1733 and Thr1833, all of which are in CBP's CH1 and CH2/CH3 domains, which interact with ETS1 [98].
In this article, we develop a stage-structured population model of these two species to explore (i) whether their circadian clocks impact their long-term population dynamics, (ii) which of these species is a superior competitor, and (iii) how stringent potential pest control strategies have to be to significantly impact established populations of the German cockroach.
Furthermore, the acceptance criteria required by ILSI for including data are stringent and potential outliers are confirmed as valid before entry into the database [ 39].
The FDA has stringent requirements on potential obesity drugs.
p-values after multiple testing adjustment procedure (Benjamini Hochberg) [ 66] were calculated but found to be generally too stringent, eliminating many potential TSSs.
While it is clear that we have obtained a highly stringent list of potential pathway partners of p68 and p72, with regard to separable functions (i.e. non-overlapping genes of p68 and p72) we cannot say with confidence as genes generally clustered into the same pathways as for the overlapping list.
This study was not powered to evaluate VE against CIN3+, which is the intermediate precursor to invasive cervical cancer and provides the most stringent evidence of potential cancer prevention even if CIN2+ is the surrogate endpoint used in licensure trials of HPV vaccines.
Still other complaints have been leveled by environmental groups for what they believe is the Food and Drug Administration's failure to issue more precise and stringent warnings about the potential health risks for children, pregnant women and other vulnerable groups.
But the auto loans in question, about 230 transactions totaling about $2 million, were made by the Orient Corporation, a much smaller consumer financing company affiliated with Mizuho that carried out far less stringent background checks on potential buyers, the report from the outside panel said.
Such high accuracy spectroscopy is shown to provide a stringent test of calculated potential energy and ab initio dipole moment surfaces, and therefore transition intensities calculated from first principles.
Recent limitations in supplies of RV in the USA reopened discussions on the more efficient use of available biologics, including utilization of more stringent risk assessments, and potential ID RV administration.
