For this reason, and to meet the more stringent requirements of population association studies, which require that the outcome be approximately normally distributed rather than only the residuals (Balding 2006), we have used log LVM adjusted for height and weight in this report.
Furthermore, when we apply a more stringent criteria for population-differentiation among miRNA variants, we found 8 highly population-differentiated miRNAs (HPD-miRNAs) with variants above the 99th percentile representing the top 1% of all pairwise FST estimates (FST ≥ 0.366; p < 0.05).
Other models such as paleolithic, vegeterian or vegan diets may be also healthy, however they are less realistic and more stringent for occidental populations.
The eBURST methodology appears, therefore, to have greater sensitivity for identifying recent clonal populations, or at least applies a much more stringent definition for such populations.
This was done using the strictMask files which impose stringent filters devised for population genetic analysis (available at http://www.1000genomes.org/).org/
When the goal is to simply find a set of single nucleotide polymorphisms to analyze spatially among population samples, stringent quality filtering can yield valuable data at the cost of enormous data loss.
When DNA damage occurred in G2 cells (~ 10% of the total cell population), a stringent G2 arrest was observed 2 hr post-IR, as indicated by ≥ 94% reduction in mitotic cells.
This theory required stringent conditions on the population structure [ 37, 38], attempted to obtain the basis for a new complex adaptation by pure chance, and has not been uniformly accepted [ 38, 39].
Naturally, the more nDNA loci that differentially interact with the mitochondria in the two populations, the more stringent the flow of nDNA genes from one population to the other and the stronger the presumed hybrid breakdown.
We carried out the simulations on the global data set, including all four populations, using stringent criteria, assuming selection to be 10%.
In addition, we also performed a round of less stringent selection on these populations, selecting 25% closest to the desired level, and a round of more stringent selection, selecting only the 1% of the population closest to the desired level.
