Sentence examples for stringent point of from inspiring English sources

Quantitative RT-PCR data for AAEL004188, AAEL004188 and he act5C gene used as a control by Hotopp et al. [ 5] matched the array results, as shown in figure 3. The act5C gene is, as the authors note, highly and constitutively expressed and may in fact be an overly stringent point of comparison to assess whether horizontally transferred genes are likely to be functional.

While the latest FDA guidelines from March 2015 [30] include more stringent points on quality, it is not known or clear if any of the additional suggestions made will be implemented, checked, and complied with in the future.

When we used a more stringent cut point of P<0.01 instead of P<0.05 to define genes that were increased in EGFR-transfected MCF-7 cells (576 genes in all), 28 overlapped with the mutant EGFR NSCLC signature (chance expected of seven genes, P<1E 10, one-sided Fisher's exact test).

Taking into account that phages are capable of extravasation within an hour and that tumor vasculature is more porous than normal tissue, a stringent time point of 10 minutes was used for in vivo circulation within the CPC Apc mouse model to isolate phages that first bind to the target tissue.

The findings were replicated in sensitivity analysis using an alternative, less stringent cut point of >18 to define high FRS (Supplementary Table 2).

Third, beneficial associations of MVPA with metabolic risk factors might have been missed as a result of the definition of MVPA, as suggested by the stronger, albeit non-significant, inverse associations with waist circumference, systolic blood pressure and clustered metabolic risk when we used a more stringent cut point of ≥4.0 METs, as opposed to ≥3.0 METs.

"It's overly stringent in my point of view -- not from a business point of view, but from a social point of view," Mr. Rueda said.

Using a stringent cut-off point of false discovery rate (FDR -adjusted p value<0.05 and log2(FDR -adjustedique genes (125 upregulated and 99 downregulated) were differentially expressed.

Using a stringent cut-off point of a loading of 0.5 for item inclusion [ 13], 30 of the 47 items loaded on to a factor and presented a simple structure, (i.e. no items loaded on to more than one factor).

It meets the stringent sensitivity, ease of use, and short assay time requirements for point-of-care and point-of-incidence applications.

Studies with a less stringent threshold 20 and later point of assessment 15 showed a poorer prognosis with non-recovery, highlighting the significance of arbitrary thresholds in study design.