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I then used MAST to search Drosophila proteomes for stringent matches (P < 0.00001 for each motif match).
The number of stringent matches to reference sequences went up by less than 1% in all cases (see Additional File 2, Tables S2-S7), suggesthat thet the additional effort involved in generating and combining these assemblies may not be worthwhile.
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Longfield argues the best way to tackle the problem of merry-go-round care placements is twofold: providing specialist training for foster carers – she highlights examples of such training in Ealing – and a more stringent matching process.
This comparison is based on stringent matching criteria to ensure that participants and non-participants were indeed closely comparable at least on dimensions we can observe (e.g. age, gender, tenure in the company and prior performance).
Sensitivity analyses were conducted using a more stringent matching criterion on the propensity scores (0.001).
Clearly, the choice of different specialized databases and perhaps less stringent match criteria has the potential of reducing this portion.
Notwithstanding stringent matching criteria for demographic and severity of illness data including mean blood glucose, we cannot completely exclude confounders.
Under the stringent matching criteria, it was found that the target numbers of both nematodes ranged from one to thousands.
However, because of the relatively stringent matching criteria, fewer than 2 controls per case were available in certain strata.
The matched cohort-design has been associated with selection bias when stringent matching criteria prevent some cases of SSI from being included in the study analysis (24, 25 ).
When analyzing ancient DNA sequences, it is necessary to avoid setting too stringent matching parameters, to increase the probability of having an informative result.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com