Sentence examples for stringent gene from inspiring English sources

Using this more stringent gene set, clustering further improved the separation of samples in clinically and pathologically defined groups, especially for the AD, PSP and control samples (see Figure 2A).

In conclusion, using a stringent gene set consisting of 166 probes it was possible to discriminate controls, AD and PSP cases from each other and clearly discriminates these groups from the group of FTD/PiD disease samples, i.e. a FTLD [26] group.

Filtering left us with a set of 14 stringent gene duplications.

The use of such a stringent gene selection method that uses both multiple testing correction and a fold-change cutoff did not significantly affect our conclusions.

Additional analysis was also performed using the more stringent gene set (adjusted P of < 0.1) which reduces the risk of false positive genes in GoSeq KEGG pathway analysis.

Importantly, majority of P. falciparum genes are activated only once during the infected RBC cycle attesting the importance of stringent gene regulation in stage-specific manner [ 11, 12].

We used a stringent gene-shaving strategy coupled with knowledge-based analyses to uncover changes in gene expression most relevant to biological responses.

Our rather stringent candidate gene analyses revealed several genes in the significant Chr 6 QTL regions that are associated with neurogenesis and cell proliferation.

In general, array CGH must be more stringent than gene expression analysis because it is required to detect single copy changes and, while the copy number of a gene, unlike the expression level, is expected to be identical in two samples, this is often not the case due to tumour heterogeneity and the presence of contaminating stromal cells [53].

The origin of this problem lies in the fact that, although Rep synthesis can, to a great extent, be inhibited by using stringent inducible gene expression systems, most if not all of them are "leaky" (especially in the context of replicating DNA templates).

We have also extended this study and have defined a more stringent core gene set compared to those previously published due to the comprehensive array coverage.