The use of submaximal FiO2 requires additional equipment and more stringent monitoring thus increasing expense.
These numbers indicate a gradual enrichment of high-quality, 'mappable' markers at more stringent thresholds at the expense of excluding other possibly informative markers.
But it also reflects increasingly stringent screening, paperwork and expenses for prospective foreign parents and a nationalistic reaction that has led some local officials, like those Ms. Horton faced, to hamper American adoptions.
Thus, as the criteria for calling a test result positive are made more stringent, specificity improves at the expense of sensitivity.
To control for random associations, generated p-values typically must reach "genomic" levels [15], and adopting such stringent standards is likely at the expense of weak but biologically plausible associations, especially in settings with obligate limitations to sample sizes.
Core earnings are less strict on expenses than GAAP but far more stringent than operating earnings.
As tests are performed on a large number of genes, stringent false-discovery rate control is required at the expense of detection power.
The stringent new rules, which come in the wake of the expenses scandal, are likely to provoke further objections from MPs, but all three party leaders have indicated their willingness to uphold them, in a bid to allay public anger over the allowances debacle.
In this way, important regulatory elements such as miRNA and trans-acting siRNA loci can be found, although potentially at the expense of a number of false negatives due to the stringent requirements on abundance.
However, we adopt rather stringent criteria to avoid inclusion of erroneous non-ortholog pairs, at the expense of potentially underestimating the number of true orthologs.
