On the other hand, addition of the calcium ionophor A23187 to recombinant membrane vesicles resulted in a 15% stimulation of ATP hydrolysis indicating a more stringent calcium dependence of the membrane-bound enzyme.
A variety of different SCF subassemblies can be expressed in a functional state in bacteria, which argues against a stringent client dependence on Hsp90, and no depletion of SCF components on Hsp90 inhibition has been reported.
Static and dynamic, inviscid and viscous contributions are separated, and stringent requirements for the dependence on the local voidage are found which are met by a simple model.
However, unlike the LWR, the inherent design features of the high-temperature gas-cooled reactor (HTGR) enables the HTTR meet stringent regulatory criteria without much dependence on active safety systems.
We reasoned that such stringent growth conditions might alleviate cellular dependence on HSF1, which is distinct from suspension growth conditions (Fig 7I).
It depends how stringent the cap is.
Diminishing petroleum reserves, sharp fluctuations of crude oil prices, increasingly stringent environmental regulations and the global demand for a decreased dependence on petroleum for the production of fuels and chemicals, are the main driving force for the recent renewed interest in Fischer Tropsch (FT) synthesis in academia and industry.
Although the number of GWASs has grown dramatically during the last five years [ 36, 37], GWASs have several limitations, such as small sample size, dependence on minor allele frequency and genetic effects, stringent statistical significance, and the difficulty of replication across studies [ 38].
Examining the estimates derived from expected correlations between SKAT and burden tests, it can be seen that the stronger dependence between SKAT statistics (as was seen in Fig. 1) leads here to less stringent significance thresholds for SKAT-based analysis, compared to burden tests.
