Exact(1)
In addition, since SpoIIIE can slip under force and re-engage the DNA upstream of the slipping site, constructs with a stepping-stone of 1 bp represent the most stringent crossing obstacles because 1 bp is the minimum foothold needed by the motor.
Similar(59)
Stringent cross-validation schemes outperform LOO-CV.
LOO-CV again yielded relatively poor prediction errors and selected low numbers of k nearest neighbours as compared to the more stringent cross-validation schemes due to overfitting tendencies.
Given the fact that more construction data and fewer validation data (i.e. a less stringent cross-validation) favour the selection of more complex models (cf. Additional file 1: Figure S6), model selection bias will on average be largest for LOO-CV and will decrease with larger validation data set size. Figure 4a shows that LOO-CV most severely underestimates the true error.
Hence, our high success rate was not by chance but because the stringent crosses were more likely to succeed.
I want to see farmers encouraged to engage in agri-environmental measures rather than being subject to stringent cross-compliance rules.
To look deeper into this dataset and seek potentially biologically relevant molecular mechanisms of dysbiosis, we turn to the more stringent cross-donor analysis.
Results: We test SMURFLite on all propeller and barrel folds in the mainly-beta class of the SCOP hierarchy in stringent cross-validation experiments.
We first test SMURFLite on all propeller and barrel folds in the mainly-beta class of the SCOP hierarchy in stringent cross-validation experiments.
Through stringent cross-validation experiments, we show that this predictor can generate precise annotations and that it compares well with ANCHOR, MoRFpred and MFSPSSMpred based on a carefully assembled test set derived from database annotations and scientific reports.
SMURFLite's ability to recognize beta propellers and barrels was compared with HMMER (Eddy, 1998), RAPTOR (Xu et al., 2003) and HHPred (Söding et al., 2005) in a stringent cross-validation experiment.
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