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More stringent correlation thresholds reduce the number of genes correlated to at least one other gene at or above that threshold.
In addition, as it can be seen in Figure 2, SMARCA4 correlates with SECISBP2 through GPX1, thus suggesting a stringent correlation between SMARCA4, SP1, SECISBP2, and many other mRNAs.
The stringent correlation between the frequencies of IL-2 and IFN-γ producing memory Th cells after graded stimulation with ionomycin or graded inhibition of stimulation by CsA confirms this view (Supplementary Fig. S5).
We did, however, not find the expected stringent correlation.
No stringent correlation between the amount of processing of caspase-9 and effector caspases was seen.
This stringent correlation threshold was chosen to eliminate potential spurious correlations in a coexpression network.
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The plasma parameters of the gas temperature and electron temperature revealed stringent correlations with the film composition and properties and thus can already monitor the resulting properties during the deposition process.
Less stringent correlations may still be informative.
An unsupervised hierarchical clustering analysis can then divide patients into groups based on their B-cell profiles, and stringent correlations of B-cell fingerprints with clinical, immunological and other emergent features can be identified.
To ensure only tightly correlated probes were clustered, we employed a stringent cutoff (correlation distance cutoff 0.2).
As the p-value for gene selection becomes more stringent, the correlation increases (data not shown).
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