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"Member states should not be prohibited from unilaterally introducing more stringent controls for NPS," Mr Baker argues.
Finally, because of the large number of statistical hypotheses tested in eQTL studies (all genes versus all markers) such studies notoriously suffer from high false-positive rates unless stringent controls for multiple testing are applied.
Therefore, stringent controls for the purpose of identifying non-specific binders, computational filtering and independent PPI validation methods are required.
Therefore, stringent controls for and prevention of mycoplasma contamination should be standard and should be sought before any cell experiment proof of a mycoplasma free-cell culture.
Similarly, in the parallel example of genetic association studies, several recent analyses have highlighted the need for more stringent controls for the very strong genetic confounders [ 3, 4].
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It thus provides a more stringent control for estimating the efficiency of other algorithms.
Noticeably, in all these experiments, 17XL parasites served as a stringent control for specificity of such adherence.
Knock-in Nf1 GRDCTL mice generated from this construct are a stringent control for Nf1 GRD animals.
Furthermore, we included the DNA from four healthy donors as the most stringent control for the pattern of promoter CpG island methylation in normal liver tissues.
By correlating the expression patterns of individual proteins with HB scores, we identified seven putative biomarkers of HB that survived stringent control for multiple hypothesis testing.
As a stringent control for the symptomatic set, we screened pre-operative sera from patients harbouring benign pulmonary hamartomas (PHs, 15 sera, Fig 1A).
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