Sentence examples for stringent challenge from inspiring English sources

However this was not sufficient to prevent patent infection in malaria naïve individuals in the stringent challenge model used that involves high numbers of sporozoites for infection.

In addition, mice vaccinated 3 days before challenge showed clinical signs of disease and weight loss, but most survived this stringent challenge.

We predict that, had we used higher doses of antibody, or a less stringent challenge dose, we would have observed a significant correlation between reduction in viral load and survival.

These protection data in a stringent challenge model in association with an excellent clinical profile highlight the potential of this adjuvanted H5N1 candidate vaccine as an effective tool in pandemic preparedness.

The authors did test two rather acute and rather similar perturbations without success, though the zebrafish would seem to be amenable to much more extensive and stringent challenge.

The ability to distinguish single nucleotide differences between nucleic acid targets, for example, single nucleotide polymorphisms (SNPs), is a stringent challenge for a nucleic acid target detection assay.

As interactive multimedia communications are developing rapidly on the Internet, they present stringent challenges on end-to-end (E2E) performance.

Protein dilution poses stringent challenges to timer circuits by continually diluting out timer components in proliferating cells (Figure 1A, right).

FG devices, however, are inherently vulnerable to fatal data loss through a single defect in the tunnel oxide [1], and face stringent challenges in the course of device downscaling owing to the gate-coupling concern [2].

A more stringent revegetational challenge is that following strip-mining.

Only HA or HA+NP+M2 vaccination conferred protection against a stringent virus challenge.