But the proposed threshold for shareholder action is high (more than a third of votes against the current incumbent) and the conditions stringent (the candidate must be truly independent), so it is hard to see the proposals being anything other than symbolic.
We decided to take a stringent approach to candidate pruning and eliminated candidates that did not reduce the percentage of EGFP-positive cells by more than 10% compared to the average for a LacZ control.
In Washington, which has perhaps the most stringent requirement, a candidate's credit history must be substantially related to the job under a law that took effect in 2007.
To qualify as a presidential candidate, stringent criteria must be satisfied.
Using ' q-gram filtering', which considers the number of k-mer matches within a region of dynamic programming alignment matrix, can provide a more stringent filter for candidate matches than single seeds (Rasmussen et al., 2006).
In their study, five mantle cell lymphoma cell lines were examined which may result in a more accurate and stringent selection of candidate genes compared to our data analysis in which we only used two cell lines.
With a more stringent set of candidate genes, that is, carnivore-specific Y-linked genes, the reliability of the similarity search can be improved, and the search for intronic sequences would allow for a better differentiation between gametologs on the two sex chromosomes.
The reader is also reminded that high scores correspond to high scoring candidates, stringent examiners, difficult stations, and high marks awarded.
The small number of candidates under positive selection likely reflects the high level of protein conservation between bowhead and other cetaceans as well as the stringent filtering of candidates due to data-quality concerns; all results and alignments are provided in Supplemental Folder 1.
Further to providing stringent evaluation of a candidate human vaccine in pre-clinical efficacy studies utilizing actual target animal species, the approach allows the possibility of cost reductions for the final product by increasing the scale of manufacture.
