Histological grading of ependymomas is difficult and there appears to be a less-stringent association between tumor grade and prognosis in ependymoma when compared with astrocytoma patients.
While few associations meet stringent association thresholds, further analysis of the most strongly associated variants has yielded results of interest (Arking et al, 2008; Weiss et al, 2009).
The experiments revealed a stringent association of protein and mRNA expression levels of CXCL10 and STAT1 in the tumor.
Thus, this analysis may represent a rather stringent test of the association between maternal depression and child height.
In addition, the Bonferroni correction for the number of phenotypes multiplied by the number of genes is too stringent because it tests the global null of no association between any pair of gene/trait.
However, due to the stringent parameters that we used to ensure a robust association between a truncated copy and a dated copy harboring two LTRs (see Materials and Methods), the insertion date could not be estimated for all truncated copies (Table 3).
Use of the more stringent definition of antenatal depression (EPDS> = 15) revealed a stronger association between antenatal depression and leg length in children (0.74 (0.07, 1.40)).
Using stringent MI diagnostic criteria and controlling for known MI risk factors, our results provide no support for an association between tamoxifen use and first MI after breast cancer.
The strong association between assessment and the perceived importance of anatomy was underscored by students uniformly calling for a more stringent assessment process.
By using a stringent quality control method to exclude the analysis of potentially degraded samples, we have concluded that there is no large association between colorectal adenomas status and systemic levels of proinflammatory (TNF-α, IL-6, IL-1β) or T-cell polarizing (IL-12, IL-2, IL-10, IL-4, IL-17, IFN-γ) cytokines among a subset of participants from the IRAS Colon Study.
