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Due to these computational limitations, we performed stringent analyses by Bayesian testing of alternate topologies on the former dataset, represented in Figure 2 and Table 1 (see below).
Using these more stringent analyses, 5.2 20.5% of the DCs present in the ITD+ AML samples corresponded to mDC/pDCs (Fig. 7a).
However, most of the ncRNAs identified in the more stringent analyses have evidence for interference by pseudogenes, with the exception of LINC00461.
For stringent analyses, peaks with heights lower than this threshold level were excluded from quantification.
Such stringent analyses are likely to detect fewer but more reliable sex-biased contigs.
In addition, simple, yet stringent, gating-based analyses of FRET can be performed on a flow cytometer simultaneously with data collection, allowing FRET-based cell sorting that can be used in high-throughput screens to identify interacting proteins.
The results are presented for the analyses of the stringent conditions, while data for the less stringent conditions will be given only if they principally differ from the stringent conditions.
Percentage variance accounted for (%V), together with analyses of residuals, is used as a stringent test of accuracy of prediction against observed data.
This shortens the run time further, enabling rapid mappings and analyses of pathways with varying relaxed or stringent threshold values.
SNEP analyses of all probe sets at a stringent threshold are an alternative to those of highly expressed genes at a moderate threshold for obtaining more true SFPs.
These frustrating findings of the above attempts underscore the need for stringent phenotype definition and powerful statistical gene mapping methods in genetic analyses of hypertension.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com