"We live in a climate when any of these stringent activities are seen as essentially immoral and disgusting, but if you look cross-culturally at how human organizations work, you see with exceptional frequency patterns in which young males are subjected to some kind of initiation, either more or less rigorous.
However, there are constraints on distance and orientation from the protein backbone, which are more stringent for activity toward substrates than for autophosphorylation.
Our goal was to intervene at the level of the school class, so we did a cluster randomised controlled trial with a school based stringent physical activity programme versus traditional physical education during one school year.
Because Boolean criteria do not allow such variability in the subcriteria scores as does DAS28, at any timepoint fewer patients fulfil Boolean remission due to the originally more stringent disease activity criteria.
Businesses of all kinds moan that stringent procedures depress activity.
In rich broth, i.e. under non-stringent conditions, urease activity, correlating with expression, has been described to be at its maximum in the absence of ammonium chloride, and enzymatic activity decreases with increasing ammonium concentrations [ 66].
Although the rate of partial remission, a stringent criterion for disease activity, decreased steadily over the follow-up period, other measures of disease activity indicated that most of the substantial improvement achieved over the first 28 weeks of treatment was well maintained during the follow-up period.
The use of a recombination reporter is a stringent test of the activity of the enzyme – probably more so than attempts to directly measure breakage at the locus.
Under these less stringent criteria, the overall activity recorded with most of the studied extracts can be considered important.
