Sentence examples for stringent activation from inspiring English sources

However, these studies have typically employed less stringent activation contrasts than the ones employed here, which tested for selective or common effects across multiple incentive conditions, and also required increased activation relative to baseline (i.e., no-incentive) blocks.

The efficient removal of extracellular ATP by CD39 together with the low affinity of P2X7 for ATP [[ 27]] represent a stringent activation threshold preventing premature IL-1β release from MCs at sites of inflammation or tissue damage.

Interestingly, It has been shown that memory-like T cells are less prone to tolerization than naïve cells, most likely due to their less stringent requirements for activation [28].

Naïve T cells have stringent requirements for activation and depend on a second signal, which is generally contributed by professional APCs in secondary lymphoid organs.

Owing to the limited number of APCs and the accessibility of MHCs and costimulatory molecules in vitro, a more stringent selection for activation may be imposed despite an excess of the galactosylated CII peptide.

Skeletal development and bone remodeling require stringent control of gene activation and suppression in response to physiological cues.

As CMOS devices scale into the 45 nm process window, the requirements for the individual devices become even more stringent, with levels of activation well above solid solubility with minimal dopant diffusion.

Rhx leads to activation of the stringent response by specifically inhibiting the synthesis of arginyl-tRNA.

The stringent response also leads to activation of RelE, an effective inhibitor of protein synthesis.

This finding implied that partial activation of the stringent response is sufficient to rescue the growth of cells lacking condensin in rich medium.

In the intracellular pathogen Brucella spp., the activation of the stringent response, a global regulatory network providing rapid adaptation to growth-affecting stress conditions such as nutrient deficiency, is essential for replication in the host.