Hence, the immunotherapy tested herein would have to destroy all neoplastic foci to affect a complete cure, which is perhaps too much to expect; our view is that the stringency of this system has advantages as a readout for therapeutic strategies, in the observed efficacy may be more predictive of responses in the clinic that those observed with subcutaneous tumors.
Details of a new CO2 test, the Worldwide Harmonized Light Vehicles Test Procedure (WLTP), are being finalised by the commission, but MEPs have expressed concern about the stringency of the new system.
Benefiting from the high efficiency and stringency of the ARAi system, we successfully constructed an MazF-based counterselection marker.
Specific requirements for each considered criterion, as well as the grading structure and stringency of these systems, are also analyzed.
The reasons for this variability are related to the stringency of the regulatory approval systems, technological risks, and the costs of building full-scale manufacturing facilities which influence funding needs and thus also the choice of organisational form.
Hence, the establishment of the counterselection system pARA-MazE/F not only verified the stringency of ARAi system in C. cellulolyticum but also provided an efficient inducible counterselection marker for further seamless genetic manipulation.
Great efforts to expand the number of graduates have gone hand-in-hand with budgetary stringency across the system, to make the overall strategy affordable.
The lower activity of the kdr ZFP2 zinc finger array in the B2H system may be due to low DNA-binding specificity as well as to the lower stringency of the bacterial one-hybrid (B1H) system used to select the kdr-targeted zinc finger arrays (see Discussion below).
The index is composed of nine operational design components that shape the transparency and stringency of patent systems and affect the extent to which they comply with patentability conditions.
It is reasonable to assume that the evolution of such different arrangements has a bearing on the particular signalling performance and features of the system, such as sensitivity, speed, fidelity, signal amplification, noise and control stringency.
