Sentence examples for stringency led from inspiring English sources

Nonetheless, this high stringency led to the loss of many similar genes whose function is identical.

A lower stringency led to identify 10 genes with the ModelInspector and GeneProm analyses.

Accordingly, this low stringency led to an increase in the number of clusters with large cluster sizes (Fig.  4c).

These low rhA1AT titers are obtained despite the higher selection stringency as demonstrated by the relatively higher fold amplifications and the lower selection and amplification efficiencies of the pAID*p vector (Table  2), in contrast to the study by Westwood AD et al. [ 35] where higher selection stringency led to higher recombinant protein titers in serum-containing –HT medium.

For both samples, these percentages were widely distributed, ranging 56.3 97.9% and 58.2 95.9%, respectively, because the difference in detection call stringency lead to a divergence in detection call rate across the platforms.

Increasing the stringency levels leads to the selection of genes displaying the largest expression differences and thus to an increase in Type 1 error risk.

Occasionally, however, the increased stringency might lead to prediction of fragmented domains where continuous domains have been experimentally verified, as evident in the case of the SMC proteins (see Figure 2).

Decreased search stringency may lead to false positives, but by including the proximate Oct-1 binding site and searching the upstream Atlantic salmon and human promoters at low stringency, without finding any adjacent CREB and Oct-1 motifs, we believe that the in silico predictions are reliable.

Increased stringency in filtering led to increased parity of Z:autosome expression.

In some cases, reducing the stringency of filtering led to a disproportionate increase of the TP and, thus, to an increase of the PPV.

Notwithstanding this difficulty, we showed that increasing the stringency of our methodology led to a high concordance with the FREEC-based hits.